Scientists have built a new rat intestine by combining part of the animal’s own bowel with human stem cells. One day, this method could be used in humans with intestinal problems who currently have to rely on organ transplants.
A variety of diseases, including Crohn’s disease, lead to people having short bowels, which makes it harder for their bodies to absorb nutrients. One common solution is bowel transplant, but there is a shortage of intestines and, as with all transplants, the patient’s body often rejects the new organ. For a study published today in the journal Nature Communications, researchers grew new intestines in the lab.
They used two parts: the cells of the intestine, and the structure that the cells grow on to retain the...
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